Understanding cellular pathway alterations underlying phenotypic differences in rad9-deficient Saccharomyces cerevisiae with altered SAM gene mutations.

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dc.contributor.authorKhadaroo, Muhammud Akhtar
dc.contributor.authorBurns, Trey
dc.date.accessioned2021-07-30T12:51:37Z
dc.date.available2021-07-30T12:51:37Z
dc.date.created2020
dc.description2020 Celebration of Student Research and Creativity presentationen_US
dc.description.abstractSAM1 and SAM2 genes encode for an enzyme that produces S-Adenosylmethionine (AdoMet), a methyl donor in S. cerevisiae. Previous experiments have demonstrated these genes affect chromosome stability and AdoMet availability. rad9-deficient strains were used to understand the effects on cells predisposed to an aneuploid state. Growth differences were assessed between our rad9-control and mutant strains in 1,400 conditions. We are currently studying altered growth in 201 conditions with 43 different mechanisms of action to understand how the altered conditions and SAM gene status impact cellular pathways.en_US
dc.description.urihttps://youtu.be/rVhnG7a2_Fcen_US
dc.identifier.urihttp://hdl.handle.net/11216/3862
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2020
dc.subjectSaccharomyces cerevisiae en_US
dc.subjectMutationen_US
dc.subjectGenesen_US
dc.subjectCellsen_US
dc.titleUnderstanding cellular pathway alterations underlying phenotypic differences in rad9-deficient Saccharomyces cerevisiae with altered SAM gene mutations.en_US
dc.typePresentationen_US

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