Microwave Irradiation of Heteroaryl Compounds with Tropinone for the Synthesis of Aromatase Inhibitors

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dc.contributor.authorUngar, Liat
dc.contributor.authorSeibert, Samuel
dc.date.accessioned2021-12-13T15:07:54Z
dc.date.available2021-12-13T15:07:54Z
dc.date.created2021
dc.description2021 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"Heteroaryl compounds are important molecules with extensive significance in medical chemistry. In our lab, we reacted heteroaryl compounds (4- Bromoquinolone) with tropinone using microwave irradiation at 160°C and 180°C in the presence of palladium catalyst. Techniques such as NMR, MPLC, and computer modeling were then utilized to isolate and purify the compound as well as assess its potential as an orally active drug. Overall, this research is significant because the product obtained could possibly serve as an aromatase inhibitor which would help in the treatment of breast cancer patients."en_US
dc.description.urihttps://youtu.be/j4IxLnCKN7Qen_US
dc.identifier.urihttp://hdl.handle.net/11216/4212
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2021
dc.subjectHeterocyclic compoundsen_US
dc.subjectEducation research laboratoriesen_US
dc.subjectCancer Researchen_US
dc.titleMicrowave Irradiation of Heteroaryl Compounds with Tropinone for the Synthesis of Aromatase Inhibitorsen_US
dc.typePresentationen_US

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Student Research and Creativity