Synthesis of heteroaryl molecules I80-H11 through a palladium- catalyzed heteroarylation

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dc.contributor.authorMontes X, Luis
dc.date.accessioned2021-10-26T19:33:17Z
dc.date.available2021-10-26T19:33:17Z
dc.date.created2020
dc.description2020 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"The purpose of this work is to study Heteroaryl molecules such as I80-H11 and I80-H37. The structure of this molecule includes a heterocyclic halide and a tropinone scaffold synthesized using Robinson’s one-pot, domino synthetic route. We used microwave-assisted, palladium-catalyzed direct α- heteroarylation of ketones to synthesize this derivative of the tropinone molecule followed by methods of MPLC, NMR, and computer modeling to purify, identify, and evaluate our compound. Our research will expand the scope to better synthesize heteroaryl compounds, provide insight to the roles of palladium catalyst in reactions, and practice of green chemistry which is key to have lower levels of chemical use and chemical waste. Also, aid the development of projects such as CURE and UROCC that implement researched focused approach on organic chemistry courses."en_US
dc.description.urihttps://youtu.be/2rHiuPOvHmAen_US
dc.identifier.urihttp://hdl.handle.net/11216/4070
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2020
dc.subjectMoleculesen_US
dc.subjectGreen chemistryen_US
dc.subjectPalladium catalystsen_US
dc.titleSynthesis of heteroaryl molecules I80-H11 through a palladium- catalyzed heteroarylationen_US
dc.typePresentationen_US

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