Acetone Centrifugation and Acid/Base Work Up for Palladium-catalyzed Heteroarylation of Ketones Reaction

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dc.contributor.authorLe, Thao Linh (Rosie)
dc.contributor.authorNguyen, Binh
dc.date.accessioned2021-11-11T19:24:52Z
dc.date.available2021-11-11T19:24:52Z
dc.date.created2021
dc.description2021 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"The research belongs to the CURE program which exposes students to research. 2.5 million women in the US are currently fighting against breast cancer. Fortunately, placental aromatase cytochrome exists an active site that is potential for interacting with drug inhibitors. Tropinone derivatives (I80-H40, I80- H44, and I80-HIH45) were synthesized using the microwave to yield H- bonding and interaction with the Heme group in aromatase. The reaction is catalyzed by Palladium catalysis to prevent (bishero)arylation. During the process, a new work up method by acetone and acid/base wash was found to yield a better purification of the product."en_US
dc.description.urihttps://youtu.be/wxJTrJvmvpoen_US
dc.identifier.urihttp://hdl.handle.net/11216/4144
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2021
dc.subjectBreast Cancer researchen_US
dc.subjectPalladium catalystsen_US
dc.subjectPlacental extractsen_US
dc.titleAcetone Centrifugation and Acid/Base Work Up for Palladium-catalyzed Heteroarylation of Ketones Reactionen_US
dc.typePresentationen_US

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Student Research and Creativity