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URROC- Undergraduate Research in Organic Chemistry Course Synthesis of Heteroaryl Molecule I80-H53 through Palladium Catalyzed Heteroarylation

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dc.contributor.author Watson, Elizabeth
dc.date.accessioned 2021-12-16T14:00:43Z
dc.date.available 2021-12-16T14:00:43Z
dc.date.created 2021
dc.identifier.uri http://hdl.handle.net/11216/4217
dc.description 2021 Celebration of Student Research and Creativity presentation en_US
dc.description.abstract "Our research focused on the properties of several heteroaryl molecules which had never been synthesized in the hopes that they will help find better treatment for breast cancer. 2.4 NaOtBu, 2% XPhos Pd Gen 4, 1.1 tropinone (I80), 1 heteroaryl (H53), and 2 mL of toluene molar equivalents were used in the synthesis. This mixture underwent microwave irradiation to produce the heteroaryl tropinone product. This product was purified using acetone centrifugation and acid-base extraction and then identified using NMR. The synthesized molecule may be able to function as an aromatase inhibitor and help treat hormone receptor- positive breast cancer." en_US
dc.description.uri https://youtu.be/SrImV-IM7tQ en_US
dc.language.iso en_US en_US
dc.publisher Northern Kentucky University en_US
dc.relation.ispartofseries Celebration of Student Research and Creativity;2021
dc.subject Heterocyclic compounds en_US
dc.subject Breast Cancer Research en_US
dc.subject Education research laboratories en_US
dc.title URROC- Undergraduate Research in Organic Chemistry Course Synthesis of Heteroaryl Molecule I80-H53 through Palladium Catalyzed Heteroarylation en_US
dc.type Presentation en_US


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