URROC- Undergraduate Research in Organic Chemistry Course Synthesis of Heteroaryl Molecule I80-H53 through Palladium Catalyzed Heteroarylation

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dc.contributor.authorWatson, Elizabeth
dc.date.accessioned2021-12-16T14:00:43Z
dc.date.available2021-12-16T14:00:43Z
dc.date.created2021
dc.description2021 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"Our research focused on the properties of several heteroaryl molecules which had never been synthesized in the hopes that they will help find better treatment for breast cancer. 2.4 NaOtBu, 2% XPhos Pd Gen 4, 1.1 tropinone (I80), 1 heteroaryl (H53), and 2 mL of toluene molar equivalents were used in the synthesis. This mixture underwent microwave irradiation to produce the heteroaryl tropinone product. This product was purified using acetone centrifugation and acid-base extraction and then identified using NMR. The synthesized molecule may be able to function as an aromatase inhibitor and help treat hormone receptor- positive breast cancer."en_US
dc.description.urihttps://youtu.be/SrImV-IM7tQen_US
dc.identifier.urihttp://hdl.handle.net/11216/4217
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2021
dc.subjectHeterocyclic compoundsen_US
dc.subjectBreast Cancer Researchen_US
dc.subjectEducation research laboratoriesen_US
dc.titleURROC- Undergraduate Research in Organic Chemistry Course Synthesis of Heteroaryl Molecule I80-H53 through Palladium Catalyzed Heteroarylationen_US
dc.typePresentationen_US

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Student Research and Creativity