Phosphoenolpyruvate carboxykinase genes may play critical role in embryonic development

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dc.contributor.authorDonahue, Kelsey
dc.date.accessioned2021-10-25T13:42:18Z
dc.date.available2021-10-25T13:42:18Z
dc.date.created2020
dc.description2020 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"During development, cells in vertebrate embryos differentiate to form adult tissues and organs. Many genetic signaling pathways are used by cells to communicate and coordinate their development. If these genetic signals are disrupted, birth defects can result. We identified two genes from the pck (phosphoenolpyruvate carboxykinase) family that were potentially being expressed during embryonic development. We analyzed pck gene expression with in- situ hybridization and determined the tissue layers the pck genes were expressed in by sectioning the embryos. Our results show that pck1 and 2 are expressed in the ectoderm, a tissue that forms the skin and nervous system, suggesting that these genes may play important roles in the development of the skin. Moreover, amino acid alignments of the pck genes from multiple species were completed, identifying considerable similarities in protein domains. These results contribute to our understanding of the evolution and roles the pck genes play during embryonic development."en_US
dc.description.urihttps://youtu.be/-iUFXiB4oCsen_US
dc.identifier.urihttp://hdl.handle.net/11216/4037
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2020
dc.subjectPyruvate kinaseen_US
dc.subjectEmbryologyen_US
dc.subjectSkinen_US
dc.titlePhosphoenolpyruvate carboxykinase genes may play critical role in embryonic developmenten_US
dc.typePresentationen_US

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