A Comparison of Tropinone Derivative Synthesis Protocols in an Undergraduate Research Chemistry Course Laboratory
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Northern Kentucky University
Abstract
"Heterocyclic compounds are ideal candidates for pharmaceutical compounds. They are used as mediums in the synthesis of anticancer medicines. I80- H37 is one such possible molecule created by direct heteroarylation via Palladium catalyst. I80-H37 is a heterocyclic compound featuring a tropinone scaffold with a single nitrogen group.
Physiochemical properties were analyzed using Molinspiration and Percepta software to determine the compound's active drug potential. This study compares different methods for synthesizing I80-H37 to increase production efficiency and the potential efficacy of I80-H37 as a vehicle for anticancer drug delivery."
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2021 Celebration of Student Research and Creativity presentation
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Presentation
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Heterocyclic compounds, Cancer Treatment, Pharmaceutical chemistry