A Comparison of Tropinone Derivative Synthesis Protocols in an Undergraduate Research Chemistry Course Laboratory

Abstract

"Heterocyclic compounds are ideal candidates for pharmaceutical compounds. They are used as mediums in the synthesis of anticancer medicines. I80- H37 is one such possible molecule created by direct heteroarylation via Palladium catalyst. I80-H37 is a heterocyclic compound featuring a tropinone scaffold with a single nitrogen group. Physiochemical properties were analyzed using Molinspiration and Percepta software to determine the compound's active drug potential. This study compares different methods for synthesizing I80-H37 to increase production efficiency and the potential efficacy of I80-H37 as a vehicle for anticancer drug delivery."