Molecular Docking of Novel mPGES-1 Inhibitors

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dc.contributor.authorBezold, Elise
dc.contributor.authorGilliam, Kendyl
dc.date.accessioned2021-09-20T13:09:09Z
dc.date.available2021-09-20T13:09:09Z
dc.date.created2021
dc.description2021 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"Nonsteroidal anti- inflammatory drugs (NSAIDs) are the current treatment for inflammation; however, NSAIDs have led to severe cardiovascular and gastrointestinal side effects. Therefore, there is a significant need for next generation anti-inflammatory drugs that do not present these same side effects. This poster is focused on molecular docking studies of compounds as potential inhibitors of a microsomal prostaglandin E2 (mPGES- 1), a specific enzyme within the inflammatory pathway known to prevent these severe side effects. The top docking scores will then be compared to biological data, which will lead to a structure-activity relationship that will be applied to further analogue design."en_US
dc.description.urihttps://youtu.be/PmzzO_tALS0en_US
dc.identifier.urihttp://hdl.handle.net/11216/3970
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2021
dc.subjectNonsteroidal anti-inflammatory agentsen_US
dc.subjectMolecular docking simulationsen_US
dc.subjectDrugs Side effectsen_US
dc.titleMolecular Docking of Novel mPGES-1 Inhibitorsen_US
dc.typePresentationen_US

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Student Research and Creativity