Ensuring the Integrity of an HSV-Vectored Vaccine System

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dc.contributor.advisor
dc.contributor.advisor
dc.contributor.authorAdams, Samuel
dc.date.accessioned2021-03-03T14:11:42Z
dc.date.available2021-03-03T14:11:42Z
dc.date.issued2020
dc.description2020 Celebration of Student Research & Creativity presentationen_US
dc.description.abstractHerpes simplex virus (HSV)-vectored vaccines for hepatitis C virus (HCV) were developed utilizing a bacterial artificial chromosome (BAC) system for DNA manipulations. These BAC-derived vectors allow for the rapid introduction and expression of foreign DNA in the HSV backbone. The DNA sequence of several production lots of the vaccine is currently being determined to confirm the genetic stability of the vaccine. While the initial vaccine target was hepatitis C virus, genes from any infectious virus, such as novel coronaviruses, could be inserted into this vaccine vector to generate immunity to that agent.en_US
dc.description.urihttps://www.youtube.com/watch?v=VCdyJa4qK58
dc.identifier.urihttp://hdl.handle.net/11216/3668
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.subjectHerpes simplex virusen_US
dc.subjectVaccines Biotechnologyen_US
dc.subjectHepatitis C virusen_US
dc.subjectBacterial artificial chromosomesen_US
dc.subjectGene rearrangementen_US
dc.titleEnsuring the Integrity of an HSV-Vectored Vaccine Systemen_US
dc.typePresentationen_US

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Student Research and Creativity