Synthesis of Heteroaryl Molecules Through Palladium-Catalyzed Heteroarylation

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dc.contributor.authorAsch, Kira
dc.date.accessioned2021-09-01T18:49:46Z
dc.date.available2021-09-01T18:49:46Z
dc.date.created2021
dc.description2021 Celebration of Student Research and Creativity presentationen_US
dc.description.abstract"Heteroaryl compounds are commonly used in medicinal chemistry. Most pharmaceuticals are made from heteroaryl compounds. The purpose of this project was to study bioactive heteroaryl compounds that could potentially be a breast cancer treatment due to its likelihood to inhibit aromatase, a pharmaceutical target for breast cancer. Through our research we reacted different heteroaryls with tropinone by microwave assisted, palladium- catalyzed direct heteroarylation. The products were then purified, identified, and evaluated by MPLC, NMR, and computer modeling. This study provided not only useful discoveries in cancer research, but also developments of CURE and UROCC labs for undergraduate chemistry students."en_US
dc.description.urihttps://youtu.be/0VItXeLLMDken_US
dc.identifier.urihttp://hdl.handle.net/11216/3964
dc.language.isoen_USen_US
dc.publisherNorthern Kentucky Universityen_US
dc.relation.ispartofseriesCelebration of Student Research and Creativity;2021
dc.subjectHeterocyclic compoundsen_US
dc.subjectBreast Canceren_US
dc.subjectCancer Treatmenten_US
dc.titleSynthesis of Heteroaryl Molecules Through Palladium-Catalyzed Heteroarylationen_US
dc.typePresentationen_US

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Student Research and Creativity