Seibert, SamuelRoy, AyanavUngar, Liat2021-12-082021-12-082021http://hdl.handle.net/11216/41932021 Celebration of Student Research and Creativity presentation"Microwave-assisted palladium catalyzed alpha- heteroarylation reactions were performed to join tropinone with heteroaryl halide compounds 4- bromoisoquinoline and 6- bromoquinoline to obtain potential aromatase inhibitors for the treatment of breast cancer. Computer modeling reveals that both target products show high enzyme-pocket docking scores compared to other tropinone-heteroaryl products synthesized in this course-based research lab. Herein, binding pocket interactions of various tropinone-derived compounds are compared to provide a rationale for further testing of these target products."en-USHeterocyclic compoundsEducation research laboratoriesCancer ResearchNKU Course-Based Undergraduate Research Experience: The Identification of Potential Aromatase Inhibitors Based on Computer ModelingPresentation