| dc.contributor.author |
Bezold, Elise |
|
| dc.contributor.author |
Gilliam, Kendyl |
|
| dc.date.accessioned |
2021-09-20T13:09:09Z |
|
| dc.date.available |
2021-09-20T13:09:09Z |
|
| dc.date.created |
2021 |
|
| dc.identifier.uri |
http://hdl.handle.net/11216/3970 |
|
| dc.description |
2021 Celebration of Student Research and Creativity presentation |
en_US |
| dc.description.abstract |
"Nonsteroidal anti- inflammatory drugs (NSAIDs) are the current treatment for inflammation; however, NSAIDs have led to severe cardiovascular and gastrointestinal side effects. Therefore, there is a significant need for next generation anti-inflammatory drugs that do not present these same side effects. This poster is focused on molecular docking studies of compounds as potential inhibitors of a microsomal prostaglandin E2 (mPGES- 1), a specific enzyme within the inflammatory pathway known to prevent these severe side effects. The top docking scores will then be compared to biological data, which will lead to a structure-activity relationship that will be applied to further
analogue design." |
en_US |
| dc.description.uri |
https://youtu.be/PmzzO_tALS0 |
en_US |
| dc.language.iso |
en_US |
en_US |
| dc.publisher |
Northern Kentucky University |
en_US |
| dc.relation.ispartofseries |
Celebration of Student Research and Creativity;2021 |
|
| dc.subject |
Nonsteroidal anti-inflammatory agents |
en_US |
| dc.subject |
Molecular docking simulations |
en_US |
| dc.subject |
Drugs Side effects |
en_US |
| dc.title |
Molecular Docking of Novel mPGES-1 Inhibitors |
en_US |
| dc.type |
Presentation |
en_US |