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Molecular Docking of Novel mPGES-1 Inhibitors

Show simple item record Bezold, Elise Gilliam, Kendyl 2021-09-20T13:09:09Z 2021-09-20T13:09:09Z 2021
dc.description 2021 Celebration of Student Research and Creativity presentation en_US
dc.description.abstract "Nonsteroidal anti- inflammatory drugs (NSAIDs) are the current treatment for inflammation; however, NSAIDs have led to severe cardiovascular and gastrointestinal side effects. Therefore, there is a significant need for next generation anti-inflammatory drugs that do not present these same side effects. This poster is focused on molecular docking studies of compounds as potential inhibitors of a microsomal prostaglandin E2 (mPGES- 1), a specific enzyme within the inflammatory pathway known to prevent these severe side effects. The top docking scores will then be compared to biological data, which will lead to a structure-activity relationship that will be applied to further analogue design." en_US
dc.description.uri en_US
dc.language.iso en_US en_US
dc.publisher Northern Kentucky University en_US
dc.relation.ispartofseries Celebration of Student Research and Creativity;2021
dc.subject Nonsteroidal anti-inflammatory agents en_US
dc.subject Molecular docking simulations en_US
dc.subject Drugs Side effects en_US
dc.title Molecular Docking of Novel mPGES-1 Inhibitors en_US
dc.type Presentation en_US

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